A Frozen Embryo Transfer (FET) cycle is a process where embryos that were frozen during a previous IVF cycle are thawed and then placed in the woman's uterus. This method is an option for trying to get pregnant in the future or for having siblings.
If you have multiple healthy embryos from an IVF cycle, and maybe the first transfer didn't result in pregnancy, or if there's a risk related to the uterus lining or OHSS (Ovarian Hyperstimulation Syndrome), a FET cycle might be recommended. It's also a good plan for those looking to delay pregnancy.
The success of FET largely depends on the woman's age but is also highly influenced by the freezing technique used. Suppose embryos are frozen using a method called vitrification. In that case, they have high survival rates, and the success rates of these vitrified blastocyst stage embryos are similar to those of fresh embryos. There's also no increased risk of miscarriages or abnormalities, making FET a solid option for pregnancy.
1. Preparing the endometrium (uterine lining)
- This step involves prepping the lining of your uterus to be receptive to the embryo implantation.
- Hormone medications, such as estrogen and progesterone, are usually prescribed to achieve this.
- Your doctor will monitor the growth of your endometrium through ultrasounds and blood tests to ensure it reaches an optimal thickness for implantation.
2. Thawing and assessing the embryos
- The frozen embryos are thawed using a specific technique to ensure survival.
- An embryologist will then carefully assess the quality of the thawed embryos to determine their suitability for transfer.
3. Embryo transfer
- A thin catheter is inserted through the cervix and into the uterus to transfer the selected embryo(s).
- This is a painless procedure that typically takes just a few minutes.
- You may experience mild cramping afterward, but this is generally short-lived.
4. Luteal support
- Progesterone supplements are often administered after the transfer to support the early stages of pregnancy if implantation occurs.
5. Pregnancy test
- A blood test is typically scheduled about a week or two after the transfer to check for pregnancy.
6. Follow-up appointments
- If the pregnancy test is positive, you will need to schedule prenatal checkups with your doctor to monitor the development of the fetus.
Embryos are thawed to match the stage of your menstrual cycle, ensuring they are in sync with the lining of your uterus for the best chance of success. The thawing timing is crucial and meticulously planned to match the embryo's developmental stage at freezing.
The embryos are transferred using a catheter gently passed into the uterus. The procedure is usually discomfort-free and doesn't require sedation for most women. It's a carefully done technique that aims for successful embryo implantation.
After the transfer, you'll receive specific instructions from your fertility specialist. A pregnancy blood test is scheduled about 11-14 days post-transfer to check for the presence of the hormone hCG, which confirms pregnancy. It's important to keep taking any prescribed medications and monitor for signs like bleeding or spotting.
Yes, there are two main types of support: hormonal support cycles and natural cycles. Hormonal cycles involve taking estrogen and progesterone to prepare the uterus, while natural cycles depend on the timing of natural ovulation. Sometimes, a shot of hCG is used in natural cycles to help with timing.
Organizing your medication schedule and ensuring you rest well is key. It's also wise to avoid extreme temperatures and follow a suitable diet. Planning logistics for the transfer day can help make the process as stress-free as possible.